Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own. Rats that were treated with these cell-sized microparticles developed permanent immune tolerance to grafts — including a whole limb — from a donor rat, while keeping the rest of their immune sy
Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor
Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.
Tokyo, Japan – Scientists from Tokyo Metropolitan University have discovered that Drosophila flies lose long-term memory (LTM) of a traumatic event when kept in the dark, the first confirmation of environmental light playing a role in LTM maintenance. The team also identified the specific molecular mechanism responsible for this effect. LTMs are notoriously difficult to erase; this work may lead t
A sperm enters an egg, an embryo develops and eventually a baby is born. But back up a second—how does the mother’s half-genome actually merge with the father’s half-genome to form one new human genome? Turns out researchers don’t really know that much about these relatively brief, yet crucial, incipient moments in fertilization.
It is already hard to believe that there is ice on Mercury, where daytime temperatures reach 400 degrees Celsius, or 750 degrees Fahrenheit. Now an upcoming study says that the Vulcan heat on the planet closest to the sun likely helps make some of that ice.
Simulating computationally complex many-body problems on a quantum simulator has great potential to deliver insights into physical, chemical and biological systems. Physicists had previously implemented Hamiltonian dynamics but the problem of initiating quantum simulators to a suitable quantum state remains unsolved. In a new report on Science Advances, Meghana Raghunandan and a research team at t
New research into the evolutionary history and prehistoric migrations of hyenas reveals surprising similarities between hyenas and prehistoric humans. The results from the University of Copenhagen and University of Potsdam also indicate that humans had a detrimental effect on hyena populations about 100,000 years ago.
Clearing the shelves of toilet paper might be just a way to make us feel more secure in troubling times. (Claire Mueller/Unsplash/) Jay L. Zagorsky is a senior lecturer at Questrom School of Business at Boston University. This story originally featured on The Conversation . The other day I went into Costco to buy some toilet paper . It came as a small shock when I couldn’t find a single roll. The
Nailed it! (Louis Hansel via Unsplash/) Sometimes, our DIY instinct is to use whatever is on hand to solve a problem. But not everyone can use paper clips, chewing gum, or paperweights to pick locks—or hang pictures. Save yourself a trip to the hardware store when you’re putting up shelves, assembling a new bed frame, or extracting random nails from the wall left by a previous homeowner. These fo
Plant anywhere. (Neslihan Gunaydin via Unsplash/) Eating local and in season is better for our planet and your health. Eating fresh produce from your own backyard, balcony, windowsill, or kitchen counter is even better for your wallet. Gardening has been proven to alleviate stress, too, so roll up your sleeves and get ready to grow some fresh herbs, potatoes, carrots, and other produce with these
The best part of 10th grade biology. (Depositphotos/) Humans are naturally curious. Toddlers will pick up a leaf or a handful of dirt like it’s a thrilling discovery—and isn’t it? Indulging our curiosity about the world around us with a microscope allows us to marvel at the magnificent architecture of organisms and matter. Collectors can solve mysteries of a coin’s age or the contents of a barely
A calm infant makes everybody happy. (Insung Yoon via Unsplash/) Designing a nursery for your baby is also an opportunity for you to see the world through an infant’s eyes. Hanging mobiles are a timeless fixture over cribs and changing tables that can engage your child with colors, movement, and even sounds as part of a nurturing environment. Here are four standout mobiles for tiny humans that ra
Supper’s on. (Simon Migaj via Unsplash/) We’ve all cooked a buttery egg for breakfast, only to ruin it by trying to take it off a pan on which everything sticks. No matter what kind of chef you are—whether you’re working through an Ottolenghi cookbook or making a simple chicken breast—everyone needs a set of reliable pans. There are so many brands and styles that it can be difficult to know which
As outbreaks of COVID-19 disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue worldwide, there’s reassuring evidence that children have fewer symptoms and less severe disease.
A trio of studies are the latest developments in a paradigm shift that could change how Earth history is understood. They support an assertion by a geophysicist that a once-liquid portion of the lower mantle, rather than the core, could have exceeded the thresholds needed to create Earth’s magnetic field during its early history.
Life is rife with patterns. It’s common for living things to create a repeating series of similar features as they grow: think of feathers that vary slightly in length on a bird’s wing or shorter and longer petals on a rose.